Exploring Brain Receptors: Key Players in Neural Signaling – A Systematic Review

Abstract

This review article consists of the functions of opioid receptor binding sites, mainly focusing on mu, kappa, and delta receptors, exemplifying their characters and binding affinities, utilizing a least squares non-linear regression curve fitting program that provides insights on the interaction between opioid and their subtypes. And glutamate receptors particularly the mGlu5 receptor and their role in modulating behaviour and neurobiological responses to substances like amphetamine in preclinical and clinical study. Further of the side effects of cannabis on autism symptoms revealing promising outcomes with observable improvements in various domains and around 4% reported side effects. Overall, this systematic review contains the basic information on all the receptors present in the brain including their subtypes, their location, and function. Information of opioid, glutamate and cannabis receptors in detail.