Analyzation of degraded DNA samples-The need for advancement

Abstract

DNA fingerprinting is one of the significant methods incorporated while forensic investigation. It is considered the golden standard while investigating cases involving identical disputes. The methods used earlier for analysis involved the use of RFLP or STR. The methods stated proved to be of paramount importance but had a few cons involving the higher time consumption, lacking in specificity, being a dominant marker, and most significant being the marker dominant. The issues stated added on to the problem of analysis of degraded blood samples, which is the most common evidence found on the scene of occurrence. To solve this issue, methods involving the use of cloning via gel electrophoresis by using Sequence Characterized Amplified Region technique that enhanced the performance and make it appropriate for the co-dominant gene. The techniques such as SNP’s and SCAR can be used, for analyzing the degraded blood sample, proving to be of paramount importance  as a technique.