Cognitive Performance in Children with Refractory Mesial Temporal Sclerosis (MTS) – an Indian Experience

Abstract

The aim of the present study was to assess the effect of depression on cognitive performance in children with Mesial Temporal Sclerosis (MTS). Thirty-six MTS children were included in the study, and the subjects were set up by a median split of the scores obtained on the Centre for Epidemiological Studies – Depression Scale for Children (CES-DC), high depression (N = 15) and low depression (N = 21). The National Institute of Mental Health and Neurosciences (NIMHANS) Neuropsychological Battery was employed. High depressive subjects displayed impairment in verbal and visual memory functions. Overall, it was revealed that there is a significant relationship between the depression score and cognitive performance. It was concluded that high depression is associated with bi-temporal involvement of the brain.